Yang Research Group

Current lab members:

Portrait (Xiaofeng)Xiaofeng Gu, M.D., Ph.D.: Assistant Researcher   [Email]

Xiaofeng Gu obtained his M.D. and Ph.D. from Shanghai Medical University where he worked on cytogenetic and molecular genetic abnormalities in childhood leukemia and other hematologic disorders. He joined the Yang lab in 2002 and his research has focused primarily on the pathogenesis of Huntington’s disease in mouse models and the application of BAC-transgenics and other new technologies to generate mouse models of human diseases.


Portrait (Nan)Nan Wang, Ph.D.: Project Scientist   [Email]

Nan Wang received her doctoral degree in Molecular and Biochemical Nutrition from the University of California at Berkeley. Her current research focuses on the pathological cell-cell interactions in Huntington’s disease and determining how mutant huntingtin affects cortical and striatal neuronal function and communication with the goal of identifying therapeutic targets that may normalize cellular miscommunication to help slow the progression of the disease.


Portrait (Daniel)C.Y. Daniel Lee, Ph.D.: Postdoctoral Scholar   [Email]

Daniel Lee received his bachelor’s and master’s degrees from National Taiwan University. He received his doctoral degree from the Department of Neuroscience at Case Western Reserve University, where he trained in Gary Landreth’s lab and focused on Alzheimer’s disease. His current work is focused on understanding the pathogenesis of HD and identifying the genetic and small molecule modifiers of HD using high-throughput high-content screenings.


Portrait (Chris)Chang (Chris) Park, Ph.D.: Postdoctoral Scholar  [Email]

Chang (Chris) Park recently received his doctoral degree in Neuroscience from the University of California, Los Angeles as a graduate student in the Yang lab. As a postdoctoral scholar in the lab, he is continuing his research on the genetic and molecular mechanisms underlying the developmental and functional roles of the basal ganglia circuitry in neuropsychiatric disorders and addiction. And yes, he knows how to pipette.


Portrait (Matt)Matthew B. Veldman, Ph.D.: Postdoctoral Scholar   [Email]

Matt Veldman received his Ph.D. from the University of Michigan Neuroscience Program with  Daniel Goldman, focusing on  mechanisms of nerve regeneration in zebrafish. This was followed by postdoctoral research in Shuo Lin’s laboratory at UCLA working on cardiovascular and hematopoietic development in zebrafish. In the Yang lab, Matt will be developing transgenic tools to study mouse brain circuitry as part of the BRAIN Initiative project.


portrait-chunniChunni Zhu, Ph.D.:  Postdoctoral Scholar  [Email]

Chunni Zhu received her doctoral degree from University of Adelaide, Australia.  She worked on blood-brain barrier drug delivery and neurodegenerative disease, including Parkinson’s and Huntington’s, in Dr William Pardridge and Dr Marie-Francoise Chesselet labs at UCLA as a postdoctoral fellow and assistant researcher.  In the Yang lab her research will be focused on systematically testing the top candidate genes identified from previous systems biology studies in order to establish the causal relationships among HTT CAG length-dependent molecular network genes, and as a result to elucidate novel disease mechanisms and therapeutic targets for HD.


Portrait (Jeff R.)Jeffrey Richman: Graduate Student  [Email]

Jeff Richman did his undergraduate study at The Scripps Research Institute in Jupiter, FL, where he studied the post-translational modification of microtubules within the brain. Currently, Jeff is a graduate student in the lab studying the role of huntingtin-interacting proteins on Huntington’s disease pathogenesis.



Portrait (Matt S)Matthew Stricos:  Staff Research Associate  [Email]

Matthew Stricos received his bachelor’s degree in Neuroscience from the University of California, Los Angeles.  While there, he completed a student research project in Dr. Yang’s lab defining mutant huntingtin aggregate morphology in a cell-based seeding assay.  Currently in the lab, he is providing technical support for the in vivo validation of key mutant huntingtin modifiers identified through our previous system biology studies.

Former lab members:

Portrait (Linna)Linna Deng B.Sc.: Visiting Graduate Student

Currently: Ph.D. Student at Peking University, Beijing.


Young Kim 2 (portrait)Young Kim, Ph.D.:  Postdoctoral Scholar

Currently: will update


Anthony Dagget, Ph.D.: MSTP Student

Currently: Medical Student at the David Geffen School of Medicine, UCLA.


Portrait (Yijun)Yijun Cui, Ph.D.: Postdoctoral Scholar

Currently: will update


Former Lab - XiaoHongXiao-Hong Lu, M.D., Ph.D.: Assistant Researcher

Currently: Assistant Professor in the Department of Pharmacology at Louisiana State University in Shreveport


Former Lab - MichelleMichelle Gray, Ph.D.: Postdoctoral Scholar

Currently: Assistant Professor in the Department of Neurology at the University of Alabama at Birmingham


 Jeff Cantle, Ph.D.: Graduate StudentFormer Lab - Jeff

Currently: will update


Former Lab - ErinErin Greiner, Ph.D.: Graduate Student

Currently: Postdoctoral Scholar in Jeffery Kelly’s lab at the Scripps Research Institute


Former Lab - TaraTara Murphy-Weitz, Ph.D.: Graduate Student

Currently: Postdoctoral Scholar in Terrence Town’s lab at USC


Former Lab - BrianBrian Wilburn, Ph.D.: Graduate Student

Currently: Senior Manager at Amgen


Former Lab - DynaDyna Shirasaki, Ph.D.: Graduate Student

Currently: Postdoctoral Scholar in Joseph Loo’s lab at UCLA


Former Lab - Mary KayMary Kay Lobo, Ph.D.: Graduate Stduent

Currently: Assistant Professor in the Department of Anatomy and Neurobiology at University of Maryland School of Medicine


Portrait (Monica)Monica Lee: Staff Research Associate

Currently: will update


Former Lab - SusanaSusie Sandoval-Miller: Staff Research Associate

Currently: Medical Student at the Keck School of Medicine of USC


Former Lab - RichardRichard Zhang: Staff Research Associate

Currently: Medical Student at the University of Pittsburgh School of Medicine


Former Lab - VictorVictor Lo: Staff Research Associate

Currently: Neurosurgeon at the University of Texas Health Science Center at Houston

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