Xiaofeng Gu, M.D., Ph.D.: Assistant Researcher [Email]
Xiaofeng Gu obtained his M.D. and Ph.D. from Shanghai Medical University where he worked on cytogenetic and molecular genetic abnormalities in childhood leukemia and other hematologic disorders. He joined the Yang lab in 2002 and his research has focused primarily on the pathogenesis of Huntington’s disease in mouse models and the application of BAC-transgenics and other new technologies to generate mouse models of human diseases.
Nan Wang, Ph.D.: Project Scientist [Email]
Nan Wang received her doctoral degree in Molecular and Biochemical Nutrition from the University of California at Berkeley. Her current research focuses on the pathological cell-cell interactions in Huntington’s disease and determining how mutant huntingtin affects cortical and striatal neuronal function and communication with the goal of identifying therapeutic targets that may normalize cellular miscommunication to help slow the progression of the disease.
C.Y. Daniel Lee, Ph.D.: Postdoctoral Scholar [Email]
Daniel Lee received his bachelor’s and master’s degrees from National Taiwan University. He received his doctoral degree from the Department of Neuroscience at Case Western Reserve University, where he trained in Gary Landreth’s lab and focused on Alzheimer’s disease. His current work is focused on understanding the pathogenesis of HD and identifying the genetic and small molecule modifiers of HD using high-throughput high-content screenings.
Chang (Chris) Park, Ph.D.: Postdoctoral Scholar [Email]
Chang (Chris) Park recently received his doctoral degree in Neuroscience from the University of California, Los Angeles as a graduate student in the Yang lab. As a postdoctoral scholar in the lab, he is continuing his research on the genetic and molecular mechanisms underlying the developmental and functional roles of the basal ganglia circuitry in neuropsychiatric disorders and addiction. And yes, he knows how to pipette.
Matthew B. Veldman, Ph.D.: Postdoctoral Scholar [Email]
Matt Veldman received his Ph.D. from the University of Michigan Neuroscience Program with Daniel Goldman, focusing on mechanisms of nerve regeneration in zebrafish. This was followed by postdoctoral research in Shuo Lin’s laboratory at UCLA working on cardiovascular and hematopoietic development in zebrafish. In the Yang lab, Matt will be developing transgenic tools to study mouse brain circuitry as part of the BRAIN Initiative project.
Jeffrey Richman: Graduate Student [Email]
Jeff Richman did his undergraduate study at The Scripps Research Institute in Jupiter, FL, where he studied the post-translational modification of microtubules within the brain. Currently, Jeff is a graduate student in the lab studying the role of huntingtin-interacting proteins on Huntington’s disease pathogenesis.
Matthew Stricos: Staff Research Associate [Email]
Matthew Stricos received his bachelor’s degree in Neuroscience from the University of California, Los Angeles. While there, he completed a student research project in Dr. Yang’s lab defining mutant huntingtin aggregate morphology in vitro. Currently in the lab, he is providing technical support for the in vivo validation of key mutant huntingtin modifiers identified through our previous system biology studies.
Weili Yang, Ph.D.: Postdoctoral Scholar [Email]
Weili Yang received her doctoral degree in Neuroscience from the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences. In the Yang lab, Weili will use single cell imaging technology to study neuronal dysfunction and degeneration in multiple HD mouse models, and correlate progressive degeneration to molecular marker.
Yichu Du: Visiting Graduate Student [Email]
Yichu Du received her bachelor’s and master’s degrees in Clinical Medicine from Harbin Medical University in China. She is a Ph.D. candidate in Neurology at Zhejiang University, and a visiting graduate researcher in the Yang lab. Her current work is focused on establishing a BAC transgenic mouse model of Spinocerebellar ataxia to further understand the mechanism of the disease.
Lucia Yang: Undergraduate Student [Email]
Lucia Yang is a third year undergraduate Neuroscience major. With the help of Dr. Nan Wang, her current projects aim to develop and execute chromatin sequencing protocols, as well as mouse models to study specific molecular targets in Huntington’s disease pathology.
Dasha Masalitina: Undergraduate Student [Email]
Dasha Masalitina is an undergraduate student at University of California, Los Angeles, studying Neuroscience and minoring in Biomedical research. Under the supervision of Chris Park, she is working on understanding the molecular mechanisms that regulate striatal function in operant conditioning behavior patterns.
Amy Pai: Undergraduate Student [Email]
Amy Pai is an undergraduate student at the University of California, Los Angeles, majoring in Neuroscience. Under the supervision of Matthew Veldman, she is optimizing tools for in vivo fluorescence visualization of sparsely labeled neuronal populations.