Huntington's Disease

Uncovering circuits, cells, and molecular pathways underlying the pathogenesis of Huntington’s disease, with the goal of finding therapeutics targets.

Basal Ganglia Circuitry

Studying basal ganglia circuitry to shed light on normal behavior, psychiatric disorders, and addiction.

Latest Lab News and Highlights

The Yang lab's latest Neuron publication, "N17 Modifies Mutant Huntingtin Nuclear Pathogenesis and Severity of Disease in HD BAC Transgenic Mice."
The Yang lab's recent Science Translation Medicine publication, "Targeting ATM ameliorates mutant Huntingtin toxicity in cell and animal models of Huntington’s disease."
[go to Publications for more info]
The Yang lab receives a BRAIN Initiative Award from NIH
Yang lab's recent papers on N17 and ATM highlighted in HD Buzz
Yang lab's research highlighed in the NINDS Director's Blog
[go to Media for more Info]
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